The isochore patterns of invertebrate genomes
نویسندگان
چکیده
منابع مشابه
The Global Invertebrate Genomics Alliance (GIGA): developing community resources to study diverse invertebrate genomes.
Over 95% of all metazoan (animal) species comprise the "invertebrates," but very few genomes from these organisms have been sequenced. We have, therefore, formed a "Global Invertebrate Genomics Alliance" (GIGA). Our intent is to build a collaborative network of diverse scientists to tackle major challenges (e.g., species selection, sample collection and storage, sequence assembly, annotation, a...
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The mouse Surfeit locus contains six sequence-unrelated genes (Surf-1 to -6) arranged in the tightest gene cluster so far described for mammals. The organization and juxtaposition of five of the Surfeit genes (Surf-1 to -5) are conserved between mammals and birds, and this may reflect a functional or regulatory requirement for the gene clustering. We have undertaken an evolutionary study to det...
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Where did vertebrate genes come from? Here we address this question by analyzing eight completely sequenced land vertebrate genomes and six completely sequenced invertebrate genomes. Approximately 70% of the vertebrate genes can be found in the six invertebrate genomes with the standard homology search criteria (denoted as V.MCL), another approximately 6% can be found with relaxed search criter...
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The human genome is a mosaic of isochores, which are long DNA segments (z.Gt;300 kbp) relatively homogeneous in G+C. Human isochores were first identified by density-gradient ultracentrifugation of bulk DNA, and differ in important features, e.g. genes are found predominantly in the GC-richest isochores. Here, we use a reliable segmentation method to partition the longest contigs in the human g...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2009
ISSN: 1471-2164
DOI: 10.1186/1471-2164-10-538